Below you will find information on resolving permissions issues on macOS that could prevent you from activating some PreSonus software...
1. Go into "Go" in your computers Finder menu bar and locate "Computer." From there, go into Macintosh HD (your system hard drive) /Users/Shared/Library. Right-click the "Library" folder and go to "Get Info." Below is an image that illustrates this option.
2. Once you open the "Get Info" window for "Library," you can click the padlock at the bottom right-hand corner of the window and enter your Mac password. You can then make changes to the settings. You can set each of your users, that are in the "Sharing & Permissions" section of the "Get Info" window, to "Read & Write." You should have your user name in there along with "Wheel" and "Everyone." If not, simply press the + sign to add them. Please refer to the image below.
3. Once you have set the permissions to "Read & Write," You can apply these changes to all enclosed items. Simply click the gear wheel and select "Apply to enclosed items." Below is an image that illustrates the setting.
4. Re-open your software and try activating once more.