AU Plug-ins: Apple has developed a bridge that allows you to run AU plug-ins in Rosetta mode, if the host application is running in native Apple Silicon mode. One solution would be to use the AU version of your plug-ins if you do not want to run Studio One in Rosetta mode in order to take advantage of the native Apple Silicon mode. If you do want to run Studio One in Rosetta mode, to continue using any VST2 or VST3 plug-ins that might not natively support the Apple Silicon chip, please follow the instructions below...
With Studio One 5.4 and above, we now natively support Apple Silicon (M1, M2, etc.) processors. It is possible that you might be working with 3rd-party plug-ins, or hardware, that do not support Apple Silicon natively. If you need to switch Studio One back to "Rosetta" mode, you can do so by right-clicking the Studio One 6 app in your Applications folder and going to "Get Info." From the "Get Info" window, you can simply check the box to run in "Rosetta" mode. Do this before launching S1 Below is a screenshot of this window...